Aspirin (Acetylsalicylic Acid)
Generic Name
Aspirin
Brand Names
Ecotrin, Bayer Aspirin
Pronunciation
AS‑pir‑in
LASA Warnings
Aspirin ↔ Atropine
Pharmacologic Class
Salicylate; Antiplatelet
DEA Schedule
None
Pregnancy & Lactation
Category C (D in 3rd trimester). Avoid in lactation.
Black Box Warning
Reye’s syndrome risk: Do not use in children with viral infections.
Mechanism of Action
Irreversibly inhibits COX‑1, blocking thromboxane A₂ formation, inhibiting platelet aggregation for the life of the platelet (7‑10 days).
Receptor Binding
COX‑1 enzyme inhibition
Cellular Transport
Passive diffusion
Barrier Penetration
Pharmacokinetics
Pharmacogenomics
None
Weight‑Based Rules
Not weight‑based
Max Lifetime Dose
N/A
Organ Impairment Dosing
Special Populations
Preparation & Stability
Tablets 81 mg, 325 mg
IV Administration Rules
Dialyzable?
Highly Dialyzable
Relative Cost
$ (Low Cost)
Availability
OTC
Specialty Template
T1: Critical Care & Resuscitation